Researchers at the J. Craig Venter Institute (JCVI) in Rockville, Md., report in the online edition of Science that they pieced together the genes of Mycoplasma genitalium, the smallest free-living bacterium that can be grown in the laboratory and a common culprit in urinary tract infections.
"The 582,970 base pair M. genitalium bacterial genome is the largest chemically defined structure synthesized in the lab," lead author Daniel Gibson told ScientificAmerican.com via e-mail. (Base pairs are complementary linked nucleotide bases, such as adenine–thymine.)
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